Serum Peptidome Profiling Revealed Platelet Factor 4 as a Potential Discriminating Peptide Associated With Pancreatic Cancer Authors
نویسندگان
چکیده
Authors ́ Affiliations 1) Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstr. 27, D-04103 Leipzig, Germany 2) Department of Mathematics, Free University of Berlin, Arnimallee 6, D-14195 Berlin, Germany 3) Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany 4) Clinic of Visceral Surgery, University Hospital Leipzig, Liebigstr. 20, D-04103 Leipzig, Germany 5) Clinic of General Visceral Surgery, Hospital St. Georg Leipzig, Delitzscher Str. 141, D-04129 Leipzig, Germany
منابع مشابه
Serum peptidome profiling revealed platelet factor 4 as a potential discriminating Peptide associated with pancreatic cancer.
PURPOSE Mass spectrometry-based serum peptidome profiling is a promising tool to identify novel disease-associated biomarkers, but is limited by preanalytic factors and the intricacies of complex data processing. Therefore, we investigated whether standardized sample protocols and new bioinformatic tools combined with external data validation improve the validity of peptidome profiling for the ...
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